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分類:導(dǎo)師信息 來(lái)源:中國(guó)考研網(wǎng) 2016-07-11 相關(guān)院校:中國(guó)藥科大學(xué)
龔國(guó)清,男,1966年8月生。1987年中國(guó)藥科大學(xué)藥理專業(yè)本科畢業(yè),1990年獲藥理專業(yè)碩士學(xué)位,2004年獲得藥理學(xué)博士學(xué)位。現(xiàn)任藥學(xué)院藥理教研室副教授,藥學(xué)醫(yī)學(xué)基礎(chǔ)實(shí)驗(yàn)中心副主任。
主要研究方向:生化藥理。主要研究創(chuàng)新化合物的抗血栓作用、抗炎作用及其機(jī)理。近年來(lái)參與完成國(guó)家自然基金項(xiàng)目2項(xiàng),國(guó)家科技部新藥創(chuàng)制重大專項(xiàng)2項(xiàng);發(fā)表SCI論文10余篇;參與申請(qǐng)的發(fā)明專利6項(xiàng),其中已授權(quán)專利2項(xiàng)。
目前主持國(guó)家自然科學(xué)基金1項(xiàng),研究創(chuàng)新藥物的抗血栓多靶點(diǎn)作用分子機(jī)制;參與國(guó)家自然科學(xué)基金2項(xiàng),科技部新藥創(chuàng)制重大專項(xiàng)2項(xiàng)。
聯(lián)系郵箱:gonggq@hotmail.com,聯(lián)系電話:13951637796
近年發(fā)表的主要文章:
1.Shaochi Wang, Peng Dai, Yungen Xu, Qiufang Chen, Qihua Zhu, Guoqing Gong*(通訊作者)Design, Synthesis, and Biological Evaluation of Dabigatran
Etexilate Mimics, A Novel Class of Thrombin Inhibitors Arch. Pharm. Chem. Life Sci. 2015, 348, 595-605
2. Mei-Ling Jiang, Zhi-Xian Zhang, Yun-Zhan Li , Xin-Hui Wang, Wei Yan, Guo-Qing Gong*(通訊作者) Antidepressant-like effect of evodiamine on chronic unpredictable mild stress rats Neuroscience Letters 588 (2015) 154-158
3. Yun Yang , Xinhui Wang , Qihua Zhu , Guoqing Gong *(通訊作者), Danmeng Luo , Aidou Jiang , Liyan Yang ,Yungen Xu , Synthesis and pharmacological evaluation of novel limonin derivatives as anti-inflammatory and analgesic agents with high water solubility Bioorganic & Medicinal Chemistry Letters 24 (2014) 1851-1855
4. Xinhui Wang, Guoqing Gong*(通訊作者), Wenhui Yang, Yunzhan Li, Meiling Jiang, Linlin Li Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model Environmental Toxicology and Pharmacology 36(2013)288-295
5. Yun-Zhan Li , Guo-Qing Gong *(通訊作者), Wen-Hui Yang , Xin-Hui Wang , Mei-Ling Jiang , Yi Zhou ,Xiao-Zhi Yang , Yun-Gen Xu , Guang-Wei He Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models Thrombosis Research 131 (2013) 425-435
6. Yi Zhou, Guoqing Gong*(通訊作者), Wenhui Yang, Yin Wang, Jing Xu, Yungen Xu The cardioprotective effect of TG-6, a newly synthesized compound, on ischemia-reperfusion injury in rats European Journal of Pharmacology 683 (2012) 190-196
7. Xiao-Zhi Yang, Wen-Hui Yang , Yun-Gen Xu* , Xiao-Juan Diao, Guo-qing Gong**(通訊作者) Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activitys European Journal of Medicinal Chemistry 57 (2012) 21-28
8. Lu Jin, Xiang-Min Jiang, Ping Du, Jing Xu, Guo-qing Gong**(通訊作者), Qiu-juan Wang, Yun-gen Xu* Synthesis and Na+/H+ exchanger inhibitory activityof benzoylguanidine derivatives. European Journal of Medicinal Chemistry,2011,46:4107-4116
參加編寫的專著:
Evidence-based Anticancer Materia Medica (ISBN 978-94-007-0525-8) (Chapter 9 An Evidence-based perspective of Hedyotis Diffusa or Oldenlandia (Sprending Hydyotis) for cancer Patients p179-192,) Springer Dordrecht Heidelberg London New York 2011.3.
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