中國藥科大學(xué)

儲(chǔ)衛(wèi)華，男，博士，中國藥科大學(xué)生命科學(xué)與技術(shù)學(xué)院微生物教研室副教授，生物學(xué)專業(yè)碩士生導(dǎo)師。中國微生物學(xué)會(huì)永久會(huì)員，江蘇省生物化學(xué)學(xué)會(huì)會(huì)員。南京農(nóng)業(yè)大學(xué)國家重點(diǎn)學(xué)科動(dòng)物醫(yī)學(xué)博士畢業(yè)；曾在南京理工大學(xué)化工學(xué)院生物工程系、美國德州州立大學(xué)生物學(xué)系從事博士后研究。主要從事微生物與免疫學(xué)、生物制藥方面的教學(xué)與科研工作。先后參與或主持國家863計(jì)劃、江蘇省三項(xiàng)工程、江蘇省自然科學(xué)基金、國家質(zhì)檢總局等課題10余項(xiàng)，作為發(fā)明人申請(qǐng)國家發(fā)明專利7項(xiàng)；發(fā)表論文40余篇，其中SCI收錄18篇。

研究方向與興趣：

1、腸道微生物與微生態(tài)制劑

2、細(xì)菌耐藥性及耐藥性抑制劑研究

3、細(xì)菌群體感應(yīng)及作為藥物靶標(biāo)的研究

代表性論文(SCI)：

1、Weihua Chu, Shuxin Zhou, Wei Zhu & Xiyi Zhuang Quorum quenching bacteria Bacillus sp. QSI-1 protect zebrafish (Danio rerio) from Aeromonas hydrophila infection. Scientific Reports, 2014，4 : 5446 DOI: 10.1038/srep05446(SCI, 5.078)

2、Weihua Chu, Shuxin Zhou, Yan Jiang, Wei Zhu and Xiyi Zhuang. Effect of Traditional Chinese Herbal Medicine with Antiquorum Sensing Activity on Pseudomonas aeruginosa," Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 648257, 7 pages, 2013. doi:10.1155/2013/648257 （SCI，2.175)

3、Weihua Chu, Tesfalem R. Zere, Mary M. Weber, Thomas K. Wood, Marvin Whiteley, Benjamin Hidalgo-Romano, Ernesto Valenzuela Jr, and Robert J.C. McLean*, Indole production promotes Escherichia coli mixed culture growth with Pseudomonas aeruginosa by inhibiting quorum signaling, Applied and Environmental Microbiology, 2012，Vol. 78, No. 2. 78: 411-419(SCI, 3.829).

4、Weihua Chu*, Fei Lu, Wei Zhu， Kang Chuntao. Isolation and characterization of new potential probiotic bacteria based on quorum-sensing system. Journal of Applied Microbiology, 2011，110, 202–208， DOI: 10.1111/j.1365-2672.2010.04872 x(SCI,2.386).

5、Weihua Chu, Vattem DA, Maitin V, Barnes MB, McLean RJ. Bioassays of quorum sensing compounds using Agrobacterium tumefaciens, and Chromobacterium violaceum, Methods Mol Biol. 2011; 692: 3-19(SCI).

6、Faping Tu, Weihua Chu*, Xiyi Zhuang, Chengping Lu. Effect of oral immunization with Aeromonas hydrophila ghosts on protection against experimental fish infection. Letters in Applied Microbiology. 2010，50(1): 13-17. Online: Sep 23 2009, DOI: 10.1111/j.1472-765X.2009.02746.x. (SCI 1.647)

7、Chu Wei-hua*, Zhu Wei. Isolation of Bdellovibrio as biological therapeutic agents used for the treatment of Aeromonas hydrophila infection in fish. Zoonoses and Public Health, 2010,57(4): 258-264, Online: Mar 26 2009 12:37PM, DOI: 10.1111/j. 1863-2378.2008.01224.x (SCI 2.22)

8、Chu Weihua, Lu Chengping. In vivo fish models for visualizing Aeromonas hydrophila invasion pathway using GFP as a biomarker. Aquaculture. 2008，277(3-4): 152-155 (SCI 2.044)

9、Chu Weihua. Optimization of extracellular alkaline protease production from species of Bacillus. Journal of industrial microbiology & biotechnology. 2007，34(3)：241-245 (SCI)

10、Chu Weihua. Adjuvant effect of propolis on immunization by inactivated Aeromonas hydrophila in Carp (Carassius auratus gibelio)，F(xiàn)ish and Shellfish Immunology，2006，21(1)：113-117 (SCI)

聯(lián)系方式：中國藥科大學(xué)生命科學(xué)與技術(shù)學(xué)院微生物教研室，電話：13921443282，E-mail:chuweihua@cpu.edu.cn