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分類:導(dǎo)師信息 來源:西南大學(xué)生命科學(xué)學(xué)院 2018-12-10 相關(guān)院校:西南大學(xué)
西南大學(xué)生命科學(xué)學(xué)院研究生導(dǎo)師李禮介紹如下:
李禮 博士,男,生于1981年9月。西南大學(xué)生命科學(xué)學(xué)院研究員、博士生導(dǎo)師,重慶市青年拔尖人才、重慶市“巴渝學(xué)者”特聘教授。
個(gè)人簡歷:
2000.09-2005.06 復(fù)旦大學(xué)公共衛(wèi)生學(xué)院 學(xué)士學(xué)位
2007.01-2011.05 香港科技大學(xué)生物化學(xué)系 博士學(xué)位
2011.05-2012.02 香港科技大學(xué)生物化學(xué)系 博士后
2012.02-2013.06 西南大學(xué)生命科學(xué)學(xué)院 特聘教授
2013.06-至今 西南大學(xué)生命科學(xué)學(xué)院 研究員
主持的科研項(xiàng)目:
1)國家自然科學(xué)基金面上項(xiàng)目(2項(xiàng))
2)國家自然科學(xué)基金青年項(xiàng)目
3)科技部973計(jì)劃子課題
4)中央高;緲I(yè)務(wù)經(jīng)費(fèi)重大項(xiàng)目
5)西南大學(xué)人才引進(jìn)啟動(dòng)基金
主要研究方向:
以斑馬魚為模式生物:
1)血液細(xì)胞發(fā)育的分子調(diào)控機(jī)制。
2)細(xì)菌感染過程中,巨噬細(xì)胞和粒細(xì)胞的行為、功能和相關(guān)的分子機(jī)理。
3)組織再生過程中,巨噬細(xì)胞和粒細(xì)胞的行為、功能和相關(guān)的分子機(jī)理。
個(gè)人榮譽(yù):
1)2015年入選重慶市青年拔尖人才。
2)2015年獲聘為重慶市“巴渝學(xué)者”特聘教授。
3)2014年入選重慶市高等學(xué)校青年骨干教師資助計(jì)劃。
4)2012年度香港科技大學(xué)理學(xué)院最佳畢業(yè)論文獎(jiǎng)。
代表性SCI學(xué)術(shù)論文:
1.Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L*. (2017) Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 10.1038/leu.2017.189. (IF=11.7)
2.Yu T, Guo W, Tian Y, Xu J, Chen J, Li L, Wen Z* (2017) Distinct regulatory networks control the development of macrophages of different origins in zebrafish. Blood 129(4):509-519. (IF=13.1)
3.Hou Y, Sheng Z, Mao X, Li C, Chen J, Zhang J, Huang H, Ruan H, Luo L, Li L*. (2016) Systemic inoculation of Escherichia coli causes emergency myelopoiesis in zebrafish larval caudal hematopoietic tissue. Sci Rep. 6:36853. (IF=5.2)
4.Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z*, Zhang Y*. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood 128(3):415-26. (IF=13.1)
5.Liu C, Wu C, Yang Q, Gao J, Li L, Yang D, Luo L*. (2016) Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction. Immunity. 17;44(5):1162-76. (IF=22.8)
6.Chen J, He J, Li L, Yang D, Luo L*. (2016) Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Sci Rep. 6:26608. (IF=5.2)
7.Jia X, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang H, Zon L, Zhou Y, Chen S, Pan W*. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 25(8):946-962. (IF=12.43)
8.Jiang F, Chen J, Ma X, Huang C, Zhu S, Wang F, Li L, Luo L, Ruan H*, Huang H*.(2015) Analysis of mutants from a genetic screening reveals the control of intestine and liver development by many common genes in zebrafish. Biochem Biophys Res Commun. 460(3):838-844.
9.Shi W, Fang Z, Li L, Luo L*. Using zebrafish as the model organism to understand organ regeneration. (2015) Sci China Life Sci. 58(4): 343-351.
10. Shi Y, Zhang Y, Zhao F, Ruan H, Huang H, Luo L, Li L*. (2014) Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish. Sci Rep. Jul 7; 4:5602. (IF=5.2)
11. Yan B, Han P, Pan L, Lu W, Xiong J, Zhang M, Zhang W, Li L*, Wen Z*.(2014) Il-1 beta and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury-Induced Inflammation. The Journal of Immunology. 192 (12): 5998-6008. (IF=4.9) (*co-corresponding author)
12. Sun J, Liu W, Li L, Chen J, Wu M, Zhang Y, Leung A, Zhang W*, Wen Z*, Liao W*. Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish. (2013) Leukemia. 27(9):1913-1917. (IF=11.7)
13. Zeng Y, Xu J, Li D, Li L, Wen Z, Qu J *. (2012) Label-free in vivo flow cytometry in zebrafish using two-photon autofluorescence imaging. Optics Letters. 37(13):2490-2492.
14. Li L, Yan B, Shi Y, Zhang W, Wen Z*. (2012) Live Imaging Reveals Differing Roles of Macrophages and Neutrophils during Zebrafish Tail Fin Regeneration. Journal of Biological Chemistry. 287 (30): 25353-25360 (IF=4.5)
15. Jin H, Li L, Xu J, Zhen F, Zhu L, Liu P, Zhang M, Zhang W, Wen Z*. (2012) Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood. 119 (22):5239-5249 (IF=13.1)
16. Li L, Jin H, Xu J, Shi Y, Wen Z*. (2011) Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis. Blood. 117(4): 1359-1369 (IF=13.1)
17. Zhang Y, Jin H, Li L, Qin X, Wen Z*. (2011) cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis. Blood. 118 (15): 4093-4101. (IF=13.1)
*通訊作者
IF為JCR公布的最新期刊五年影響因子
實(shí)驗(yàn)室歡迎有志于從事血液發(fā)育及免疫功能研究的學(xué)生加入(包括保送生和調(diào)劑生)。
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