中國海洋大學

中國海洋大學海洋生命學院海洋生物系研究生導師劉晨光介紹如下：

姓名：劉晨光

學歷/職稱/職務(wù)：

博士研究生/教授（博導）/副院長

聯(lián)系方式：科學館105

郵箱：liucg@ouc.edu.cn電話：0532-82032102

地址：山東青島市魚山路5號 
 
學習工作簡歷：

學習簡歷

1986,9-1990,7曲阜師范大學生物學系 獲學士學位
1992,9-1995,7四川大學生物學系 獲碩士學位
2002,12~2005,8 高麗大學(韓國) 生命科學與技術(shù)學院 獲博士學位

工作簡歷

1995,9~1996,12 中國海洋大學 助教

1997,1~2002,12中國海洋大學 講師

1999,9~2000,2 南京大學生物化學系國內(nèi)訪問學者

          2003,1~2007,12 中國海洋大學 副教授
          2008,1~至今 中國海洋大學 教授（2008年7月獲博士生導師資格）

          2010,4~至今 國家海洋生命科學與技術(shù)人才培養(yǎng)基地 副主任

          2013,6~至今 海洋生命學院 副院長
 
科研領(lǐng)域描述：

1）海洋生物技術(shù)

是指運用海洋生物學與工程學的原理和方法，利用海洋生物或生物代謝過程生產(chǎn)有用的生物制品。該研究方向主要進行海洋生物材料（如多糖、蛋白質(zhì)（酶）、脂質(zhì)）的分離、純化、改性、鑒定及相關(guān)應(yīng)用基礎(chǔ)研究，已成功地分離純化了多種新型的海洋多糖、海洋生物酶等。

2）微/納米生物材料

是指用于對生物體進行診斷、治療、修復或替換其病損組織、器官或增進其功能的具有微納米結(jié)構(gòu)或微納米尺度的新型生物材料，已成功地制備了殼聚糖、海藻酸、透明質(zhì)酸、海蜇膠原、氧化石墨烯等多種微/納米材料。

以上研究成果在醫(yī)藥、食品和化妝品等領(lǐng)域顯示出良好的應(yīng)用前景，其中海洋生物化妝品已實現(xiàn)產(chǎn)業(yè)化并成功推向了市場。

研究興趣：

1、微/納米醫(yī)用生物材料（藥物緩釋載體）；

2、可食性微/納米材料（營養(yǎng)物運送系統(tǒng)）；

3、微/納米生物技術(shù)在化妝品方面的應(yīng)用（活性物質(zhì)載體）；

4、微生物胞外產(chǎn)物的分離、鑒定及應(yīng)用
 
代表性成果：

主要論文：

1. Qian Li, Liang Hong, Hong-guang Li*, Chen-guang Liu*. Graphene oxide-fullerene C60 (GO-C60) hybrid for photodynamic and photothermal therapy triggered by near-infrared light. Biosensors and Bioelectronics, doi: 10.1016/j.bios.2016.03.072.

2. Mazhar Ali Raja Shah Zeenat Muhammad Arif Chenguang Liu* Self-assembled nanoparticles based on amphiphilic chitosan derivative and arginine for oral curcumin delivery International Journal of Nanomedicine 2016:11 4397–4412

3. Qian Li, Chen-Guang Liu, Hong-Guang Li*. Induction of endogenous reactive oxygen species in mitochondria by fullerene-based photodynamic therapy. Journal of Nanoscience and Nanotechnology, 2016, 16:5592-5597

4. Shuai Wang, Li Zheng, Zhisong Cui, Junhui Chen, Baijuan Yang, Xiaotian Han, Chenguang Liu* Cloning and molecular characterization of a delta-6 fatty acid desaturase gene from Isochrysis sp. CCMM5001 J Appl Phycol 2016 28:921–929

5. Zhang, Pei; Zhao, Shi-Rui; Li, Jun-Xia; Hong, Liang; Raja, Mazhar A.; Yu, Le-Jun; Liu, Chen-Guang* Nanoparticles based on phenylalanine ethyl ester-alginate conjugate as vitamin B-2 delivery system Journal of Biomaterials Applications 2016, 31: 13-22

6.Zhe Chi, Guang-Lei Liu, Chen-Guang Liu, Zhen-Ming Chi* Poly(β-L-malic acid) (PMLA) from Aureobasidium spp. and its current proceedings Applied Microbiology biotechnology, 2016, 100(9):3841-3851

7.Yulong Tan, Su Ma, Chenguang Liu, Wengong Yu, Feng Han* Enhancing the stability and antibiofilm activity of DspB byimmobilization on carboxymethyl chitosan nanoparticles Microbiological Research 2015 178: 35–41

8.Li, Q., Liu, C.-G*., Yu, Y.，Separation of monodisperse alginate nanoparticles and effect of particle size on transport of vitamin E，Carbohydrate Polymers，2015 124: 274-279

9.Wen-Hao Wei, Xue-Meng Dong and Chen-Guang Liu* In Vitro Investigation of Self-Assembled Nanoparticles Based on Hyaluronic Acid-Deoxycholic Acid Conjugates for Controlled Release Doxorubicin: Effect of Degree of Substitution of Deoxycholic Acid Int. J. Mol. Sci. 2015, 16: 7195-7209

10.Mazhar Ali Raja, Chenguang Liu* and Zhenhua Huang Nanoparticles based on Oleate Alginate Ester as Curcumin Delivery System Current Drug Delivery, 2015, 12: 613-627 613

11. Li, Qian; Yu, Yu; Liu, Chenguang* Preparation and evaluation of nanoparticles with narrow size distribution for oral delivery J. Control. Release 2013, 172 DI:10.1016/j.jconrel.

12.Wu JL, Liu CG, Wang XL, Huang ZH. Preparation and characterization of nanoparticles based on histidine-hyaluronic acid conjugates as doxorubicin carriers. J Mater Sci Mater Med. 2012, 23:1921-1929.

13.Fusheng Sun Chuanxia Ju* Jiahong Chen, Sai Liu, Na Liu Keke Wang Chenguang Liu Nanoparticles Based on Hydrophobic Alginate Derivative as Nutraceutical Delivery Vehicle: Vitamin D 3 Loading Artificial Cells, Blood Substitutes, and Biotechnology, 40: 113–119

14.Qian Li, Chen-Guang Liu,* Zhen-Hua Huang, and Fang-Fang Xue Preparation and Characterization of Nanoparticles Based on Hydrophobic Alginate Derivative as Carriers for Sustained Release of Vitamin D3  J. Agric. Food Chem.;2011, 59: 1962–1967

15.JiShiqi; Zhao Rui; Yin Qi; Liu Chenguang; Zhang Xiaohua* Gel microbead cultivation with a subenrichment procedure can yield better bacterial cultivability from a seawater sample than standard plating method JOURNAL OF OCEAN UNIVERSITY OF CHINA 2012 11: 45-51

16. Xuemeng Dong, Chenguang Liu* Preparation and Characterization of Self-Assembled Nanoparticles of Hyaluronic Acid-Deoxycholic Acid Conjugates. Journal of Nanomaterials 2010, doi:10.1155/2010/906936

17.Yu-long Tan, Chen-Guang Liu* Self-aggregated nanoparticles from linoleic acid modified carboxymethyl chitosan: Synthesis, characterization and application in vitro Colloids and Surfaces B: Biointerfaces 2009 69: 178–182

獲獎：

1)2008年入選教育部新世紀優(yōu)秀人才支持計劃

2)教育部自然科學獎二等獎（2010年，第4位）

3)海洋科學技術(shù)獎二等獎(2013年，第3位）