北京大學(xué)

黃 健: 博士，副教授  

E-Mail  jhuang@bjmu.edu.cn

地址北京市海淀區(qū)學(xué)院路38號(hào)藥學(xué)院306室   郵編100191

1995 年畢業(yè)于蘭州大學(xué)，獲理學(xué)學(xué)士學(xué)位；

1998年畢業(yè)于蘭州大學(xué)，獲理學(xué)碩士學(xué)位；

2005年畢業(yè)于北京大學(xué)，獲藥物化學(xué)博士學(xué)位；

2005年至今在北京大學(xué)藥學(xué)院化學(xué)生物學(xué)系無(wú)機(jī)化學(xué)專(zhuān)業(yè)。

研究方向：細(xì)胞無(wú)機(jī)化學(xué)和無(wú)機(jī)藥物化學(xué)；研究骨質(zhì)疏松的發(fā)病機(jī)制和藥物預(yù)防；研究藥物對(duì)前列腺癌骨轉(zhuǎn)移的抑制。

近幾年發(fā)表文章:

1.王芃, 黃健*, 張?zhí)焖{(lán), 王夔*.氯化鑭抑制人轉(zhuǎn)移型雄性激素非依賴性前列腺癌細(xì)胞DU145的生長(zhǎng)和遷移. 科學(xué)通報(bào)，2010, 55(23): 2289-2295.

2.Jian huang, Xi. Wang, Tian-lan Zhang, Kui Wang. Alterations of ovariectomized rat bone and impact of non-collagenous proteins on mineralization. Joint Bone Spine, 2009, 76(2):176-183 

3.Shi Yanling, Wang Liwen, Huang Jian, Gou Baodi, Zhang Tianlan, Wang Kui. Lanthanum Suppresses Osteoblastic Differentiation Via Pertussis Toxin-Sensitive G Protein Signaling in Rat Vascular Smooth Muscle Cells. Journal of Cellular Biochemistry 2009, 108: 1184-1191

4.Wang Chen-Guang, Liao Jia-Wang, Gou Bao-Di, Huang Jian, Tang Rui-Kang, Tao Jin-Hui,  Zhang Tian-Lan, Wang Kui. Crystallization at Multiple Sites inside Particles of Amorphous Calcium Phosphate. Crystal Growth Design, 2009, 9: 2620–2626.

5.Xi Wang, Jian Huang*, Tianlan Zhang , Kui Wang. Cytoskeleton reorganization and FAK phosphorylation are involved in lanthanum (III)-promoted proliferation and differentiation in rat osteoblasts. Progress in Nature Science 

2009,19: 331-335 

6.Xi Wang, Lan Yuan, Jian Huang*, Tian-Lan Zhang*, Kui Wang. Lanthanum Enhances in vitro Osteoblast Differentiation via Pertussis Toxin-sensitive Gi Protein and ERK Signaling Pathway. Journal of Cellular Biochemistry 2008, 105: 1307-1315 

7.王熙, 黃健*, 張?zhí)焖{(lán), 王夔. La3 + 通過(guò)重組細(xì)胞骨架影響大鼠成骨細(xì)胞增殖、分化, 自然科學(xué)進(jìn)展, 2008, 18: 1053-1057 

8.Jian huang, Lan Yuan, Xi. Wang, Tian-lan Zhang, Kui Wang. Icarin and its glycosides enhance osteoblastic ,but suppress osteoclastic, differentiation and activity in vitro. Life Sciences,  2007,81(10):832-840

9.Jian Huang, Jina-Chao Zhang, Tian-Lan Zhang, Kui Wang. Icariin suppresses bone resorption activity of rabbit osteoclasts in vitro. Chinese Science Bulletin, 2007, 52(7):890-895. ‘

10.Jian Huang, Tian-Lan Zhang, Shan-jin Xu, Kui Wang, Jing Zhang, Ya-Ning Xie.. Effects of Lanthanum on Composition, Crystal Size and Lattice Structure of Femur Bone Mineral of Wistar Rats. Calcif Tissue Int， 2006 78（4）:241–247

11.黃健, 張金超,張?zhí)焖{(lán), 許善錦,王夔. 淫羊霍苷對(duì)破骨細(xì)胞骨吸收功能的影響及其作用機(jī)制研究. 科學(xué)通報(bào),  2006, 51(24):2851-2856