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分類:導(dǎo)師信息 來(lái)源:中國(guó)考研網(wǎng) 2015-02-09 相關(guān)院校:中國(guó)藥科大學(xué)
黃鳳杰,女,博士,副教授,中國(guó)藥科大學(xué)微生物教研室
主要從事微生物和生物制藥的教學(xué)和科研工作,研究方向,天然產(chǎn)物的分離純化,藥物治療學(xué)的機(jī)理研究,與糖尿病有關(guān)的藥理學(xué)試驗(yàn)方法和代謝調(diào)控機(jī)制基本研究工作。主持了1項(xiàng)國(guó)家自然科學(xué)基金資助項(xiàng)目、1項(xiàng)江蘇省教育廳資助項(xiàng)目、1項(xiàng)國(guó)家重點(diǎn)實(shí)驗(yàn)室資助項(xiàng)目和1項(xiàng)中國(guó)藥科大學(xué)人才引進(jìn)基金項(xiàng)目,參與了1項(xiàng)國(guó)家海洋863計(jì)劃資助,2項(xiàng)國(guó)家自然科學(xué)基金資助,1項(xiàng)教育部博士點(diǎn)基金資助等多項(xiàng)課題的研究,發(fā)明專利兩項(xiàng),在國(guó)內(nèi)外核心刊物及SCI期刊發(fā)表論文20余篇,發(fā)明專利2項(xiàng)。2011年被推選為江蘇省“青藍(lán)工程青年骨干教師”培養(yǎng)對(duì)象,2006年,“鯊魚(yú)肝活性肽S-8300的純化與結(jié)構(gòu)及其防治糖尿病的作用”獲得江蘇省優(yōu)秀博士論文。
主要經(jīng)歷
2002.9—2005.6 中國(guó)藥科大學(xué) 微生物與生化藥學(xué) 博士
2010.9-2011.9 加拿大多倫多大學(xué)國(guó)家公派訪問(wèn)學(xué)者
主持科研項(xiàng)目
1.中國(guó)藥科大學(xué)引進(jìn)人才啟動(dòng)基金資助,鯊魚(yú)肝低分子多肽抗糖尿病活性物質(zhì)研究
2. 國(guó)家自然科學(xué)基金資助,鯊肝S-8300防治糖尿病作用機(jī)制及其基因克隆表達(dá)研究
3.江蘇省教育廳資助,重組S-8300防治糖尿病活性研究
4.天然藥物活性組分與藥效國(guó)家重點(diǎn)實(shí)驗(yàn)室科研項(xiàng)目資助,鹿角脫盤(pán)多肽CPU2206防治糖尿病作用及其機(jī)制研究
參與科研項(xiàng)目
1. 國(guó)家海洋863計(jì)劃資助,Ⅰ類抗肝炎新藥鯊肝刺激物質(zhì)HSS的臨床前研究
2. 國(guó)家自然科學(xué)基金資助,鯊肝HSS的一級(jí)結(jié)構(gòu)、基因克隆與防治肝炎的作用機(jī)制
3. 國(guó)家自然科學(xué)基金資助,三明治式抗腫瘤基因靶向載體技術(shù)的研究
4. 教育部博士學(xué)科點(diǎn)專項(xiàng)基金,重組水蛭素III的新用途與新劑型研究
主要論著
1. Qian Sheng Pan, Zhi Ping Fang and Feng Jie Huang. Identification, localization and morphology of APUD cells in gastroenteropancreatic system of stomach-containing teleosts. World Journal of Gastroenterology, 2000; 6(6): 842-847
2 Lü Zheng-Bing, HUANG Feng-Jie, LI Qian, YE Bo-Ping, WU Wu-Tong. Protective Effects of Shark Stimulator Substance (sHSS) against Acute Hepatic Injury Induced by APP in Mice. ACTA BIOCHIMICA et BIOPHYSICA SINICA, 2003; 35(11): 1051
3.Fengjie Huang, Wutong, Wu. Antidiabetic effect of a new peptide from squalus mitsukurii liver (S-8300) in Alloxan-induced diabetes. Clinical and Experimental Pharmacology and Physiology, 2005, 32: 521-525.ISSN:0305-18709
4.Fengjie Huang, Wutong, Wu. Antidiabetic effect of a new peptide from squalus mitsukurii liver (S-8300) in Streptozotocin-induced diabetes. Journal of Pharmacy and Pharmacology, 2005,57: 1575-1580. ISSN: 0022-3573
5. Feng-Jie Huang,Zheng-Bing Lv, Qian Li, Li-Jun Wei,Liang Zhang, Wu-Tong Wu. Study on Hepatoprotective Effect of Peptide S-8300 from Shark Liver. World Journal of Gastroenterology, 2005;11(12):1809-1812; ISSN 1007-9327
6.Advances in biopharmaceutical technology in china. Chapter 2and Chapter 20, September, 2006, Society for industrial microbiology and BioPlan Associates, Inc.
7. Fengjie Huang and Wutong Wu. Study on the antidiabetic mechanism of a shark liver peptide,S-8300, in alloxan-induced diabetes. Journal of Pharmacy and Pharmacology 2009; 61: 789–794
8 Huang F, Wu W. Purification and characterization of a new peptide (S-8300) from shark liver. J Food Biochem 2010; 34(5):962-970
9.A. Maharaj, L. Zhu, F. Huang, H. Qiu, H. Li, C. Y. Zhang, T. Jin, Q. Wang.Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes. Diabetologia (9 February 2012), pp. 1-11, doi:10.1007/s00125-012-2464-x.
10. Fang Zhao*, Fengjie Huang*, Mengxiong Tang, Xiaoming Li, Nina Zhang, Akis Amfilochiadis, Yiming Li, Renming Hu, Tianru Jin ,Chun Peng, and Qinghua Wang. Nodal induces apoptosis through the activation of ALK7 signaling pathways in pancreatic INS-1 β-cells. American Journal of Physiology - Endocrinology and Metabolism. Published online before print May 1, 2012, doi: 10.1152/ajpendo.00074.2012 (Co-first author)
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