蘭州大學(xué)

學(xué)習(xí)經(jīng)歷

1998.09-2001.07：四川大學(xué)生命科學(xué)學(xué)院植物學(xué)專業(yè)，理學(xué)博士
1995.09-1998.07：四川大學(xué)生命科學(xué)學(xué)院植物學(xué)專業(yè)，理學(xué)碩士
1991.09-1995.07：四川大學(xué)生物系植物學(xué)專業(yè)，理學(xué)學(xué)士

工作經(jīng)歷

2009.10－目前：蘭州大學(xué)萃英特聘教授，博士生導(dǎo)師，蘭州大學(xué)生命科學(xué)學(xué)院
2001.10－2009.09：博士后，The University of Oklahoma，USA

教學(xué)及指導(dǎo)研究生情況

碩士研究生招生專業(yè)：植物學(xué)（071001）；方向：植物分子生物學(xué)、植物分子發(fā)育生物學(xué)、植物細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)

博士研究生招生專業(yè)：植物學(xué)（071001）；方向：植物分子遺傳學(xué)、植物分子發(fā)育生物學(xué)、植物生殖生物學(xué)

目前指導(dǎo)博士研究生5人，碩士研究生10人。

發(fā)表論文及專著

Anderson S, Johnson C, Jones D, Conrad L, Gou X, Russell SD, Sundaresan V. (2013). Transcriptomes of isolated rice gametes characterized by deep sequencing: Evidence for distinct sex-dependent chromatin and epigenetic states before fertilization. Plant Journal, 76: 729-741.

Russell SD, Gou X, Wong CE, Wang XK, Yuan T, Wei XP, Bhalla PL, Singh MB. (2012). Genomic profiling of rice sperm cell transcripts reveals conserved and distinct elements in the flowering plant male germ lineage. New Phytologist, 195: 560-573.

Du J, Yin H, Zhang S, Wei Z, Zhao B, Zhang J, Gou X, Lin H, Li J. (2012). Somatice embryogenesis receptor kinases control root development mainly via brassinosteroid-independent actions in Arabidopsis thaliana. Journal of Integrative Plant Biology, 54: 388-399.

Gou X, Li J. (2012). Activation tagging. Methods in Molecular Biology, 876. DOI: 10.1007/978-1-61779-809-2_9.

Gou X, Yin H, He K, Du J, Yi J, Xu S, Lin H, Clouse SD, Li J. (2012). Genetic evidence for an indispensable role of somatic embryogenesis receptor kinases in brassinosteroid signaling. PLoS Genetics, 8: e1002452.

Li J, Du J, He K, Gou X. (2011). Control of cell death by Receptor Kinases in Arabidopsis thaliana. In "Receptor-like Kinases in Plants: From Development to Defense (eds Birgit Kemmerling and Frans Tax)". Signaling and Communication in Plants (ed. Frantisek Baluska, Springer Publisher), Volume 13, pp79-91.

An J, Guo Z, Gou X, Li, J. (2011) TCP1 positively regulates the expression of DWF4 in Arabidopsis thaliana. Plant Signaling & Behavior, 6: 1117-1118.

Ge L, Gou X, Yuan T, Strout GW, Nakashima J, Blancaflor EB, Tian HQ, Russell SD. (2010). Migration of sperm cells during pollen tube elongation in Arabidopsis thaliana: behavior during transport, maturation and upon dissociation of male germ unit associations. Planta, 233:325-332.

Guo Z, Fujioka S, Blancaflor EB, Miao S, Gou X, Li J. (2010). TCP1 controls brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana. Plant Cell 22, 1161-1173.

Russell SD, Gou X, Wei X, Yuan T. (2010). Male gamete biology in flowering plants. Biochemical Society Transactions 38, 598-603.

Yang H, Gou X, He K, Xi D, Du J, Lin H, Li J. (2010). BAK1 and BKK1 in Arabidopsis thaliana confer reduced susceptibility to turnip crinkle virus. European Journal of Plant Pathology 127, 149-156.

Gou X, He K, Yang H, Yuan T, Clouse SD, Li J. (2010). Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics 11, 19.

Gou X, Yuan T, Wei X, Russell SD. (2009). Gene expression in the dimorphic sperm cells of Plumbago zeylanica: Transcript profiling, diversity, and relationship to cell type. Plant Journal 60, 33-47.

He K, Gou X, Powell RA, Yang H, Yuan T, Guo Z, Li J. (2008). Receptor-like protein kinases, BAK1 and BKK1, regulate a light-dependent cell-death control pathway. Plant Signaling & Behavior 3: 813-815.

Li J, Gou X. (2007). Brassinosteroids. In Handbook of plant science (Roberts, K., ed). John Wiley & Sons, Ltd, pp. 395-404.

He K, Gou X, Yuan T, Lin H, Asami T, Yoshida S, Russell SD, Li J. (2007). BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell-death pathways. Current Biology 17, 1109-1115.

Yuan T, Fujioka S, Takatsuto S, Matsumoto S, Gou X, He K, Russell SD, Li J. (2007). BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana. Plant Journal 51, 220-233.

Wei X, Gou X, Yuan T, Russell SD. (2006). A highly efficient in vitro plant regeneration system and Agrobacterium-mediated transformation in Plumbago zeylanica. Plant Cell Rep 25, 513-521.

研究方向

（1）受體激酶介導(dǎo)的細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)。受體激酶（RLKs）分布在細(xì)胞表面，從胞外環(huán)境獲取信號(hào)并傳遞到細(xì)胞內(nèi)啟動(dòng)下游的基因表達(dá)和調(diào)控，從而讓植物體對(duì)各種信號(hào)作出正確的反應(yīng)。在擬南芥中有600個(gè)以上的受體激酶，到目前為止只對(duì)其中很少一部分基因的功能有所了解。我們克隆了其中絕大部分受體激酶的全長(zhǎng)cDNA，并轉(zhuǎn)化野生型擬南芥進(jìn)行了超表達(dá)，目前正致力于解析這些受體激酶的生物學(xué)功能。

（2）植物生殖生物學(xué)。被子植物雙受精是一個(gè)復(fù)雜的過(guò)程，一個(gè)精細(xì)胞與卵細(xì)胞融合形成合子，發(fā)育成胚胎，是下一代植物的雛形；另一個(gè)精細(xì)胞與中央細(xì)胞融合形成胚乳，為胚胎發(fā)育提供營(yíng)養(yǎng)。雙受精的成敗關(guān)系到植物種群的延續(xù)，同時(shí)也關(guān)系到絕大部分農(nóng)作物的產(chǎn)量與質(zhì)量。實(shí)驗(yàn)室目前的工作主要是利用模式植物擬南芥研究雌雄生殖器官以及性細(xì)胞發(fā)育調(diào)控的分子機(jī)理，以及早期胚胎發(fā)育調(diào)控的信號(hào)途徑。

項(xiàng)目成果

實(shí)驗(yàn)室得到國(guó)家自然科學(xué)基金委員會(huì)、教育部、科技部和蘭州大學(xué)的經(jīng)費(fèi)支持。